Blood-tests Explained


Disclaimer:

This website is intended to assist with patient education and should not be used as a diagnostic, treatment or prescription service, forum or platform. Always consult your own healthcare practitioner for a more personalised and detailed opinion

CEA


At a Glance

Why Get Tested?

Primarily to monitor cancer treatment, including response to therapy and recurrence; as an indicator of the amount of cancer or size of tumor present (tumor burden) and to assist in cancer staging; occasionally as follow up to a positive screening test for cancer, to compare whether the level falls to normal (indicating that the cancer was all likely removed) after treatment for the cancer

When to Get Tested?

When you have been diagnosed with colon, pancreas, breast, lung, ovarian, medullary thyroid or other cancer prior to starting cancer treatment and then, if elevated, at intervals during and after therapy; occasionally when cancer is suspected but not confirmed – to aid in its detection

Sample Required?

A blood sample drawn from a vein in your arm; occasionally another body fluid such as fluid from the abdomen (peritoneal), the chest (pleural), or from the spinal cord (cerebrospinal, CSF)

Test Preparation Needed?

None

The Test Sample

What is being tested?

Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus). By the time a baby is born, it drops to a very low level. In adults, CEA is normally present at very low levels in the blood but may be elevated with certain types of cancer. This test measures the amount of CEA in the blood to help evaluate individuals diagnosed with cancer.

CEA is a tumor marker. Originally, it was thought that CEA was a specific marker for colon cancer, but further study has shown that an increase in CEA may be seen in a wide variety of other cancers. CEA can also be increased in some non-cancer-related conditions, such as inflammation, cirrhosis, peptic ulcer, ulcerative colitis, rectal polyps, emphysema, and benign breast disease, and in smokers. For this reason, it is not useful as a general cancer screening tool, but it does have a role in evaluating response to cancer treatment. When an individual has been diagnosed with cancer, an initial baseline test for CEA may be performed. If this level is elevated, then subsequent serial testing of CEA may be performed to monitor the cancer as the individual undergoes treatment.

How is the sample collected for testing?

A blood sample is taken by needle from a vein in the arm. Occasionally, another body fluid such as peritoneal fluid, pleural fluid, or cerebrospinal (CSF) is collected by a healthcare practitioner for testing.

Is any test preparation needed to ensure the quality of the sample?

No test preparation is needed.

The Test