Tibolone

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

 

Popular brand names:

Livifem

Drug group:

Hormone replacement therapy

Prescription needed?

Yes

 

What does it do?

Tibolone is a female sex hormone used to treat:

• Menopausal symptoms - sweating, depressed mood, decreased sex drive, and hot flushes
• Osteoporosis – used when other drugs are inappropriate or ineffective

 

How does it work?

Tibolone has both oestrogenic and progestogenic activity and can be taken without the addition of other hormones

 

How should it be used?

• Swallow the tablets whole (do not chew)
• Only use tibolone if you have not had a period for at least 12 months
• Tibolone is recommended for short-term use around the menopause

 

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

5mg daily, preferably at the same time each day

 

How quickly will it start to work?

Some improvement of symptoms within a few weeks but best results after 3 months.   
  

How long will the effects last?

A few days   
                              

When should I stop using it?

Do not stop the drug without consulting your doctor.  
                              

Is it safe for prolonged use?

Long-term use of tibolone carries an increased risk of breast cancer, venous thrombosis, heart attack, and stroke (although smaller risk compared to other forms of HRT). You will need to have regular examinations.

                                                                         

What are the possible side effects?

Tibolone is generally well tolerated.

The following have been reported:

• Less common: weight gain, ankle swelling, dizziness, stomach upset, facial hair growth, acne
• Report to your doctor before taking your next dose if you experience: vaginal bleeding or discharge, headaches, visual problems, jaundice

 

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver/kidney problems, porphyria, diabetes, high cholesterol level, or a history of breast cancer, heart attacks, stroke, or venous thrombosis
• Other medicines: phenytoin, phenobarbital, primidone, carbamazepine, rifampicin, warfarin
• Pregnancy and breast-feeding: Not prescribed
• Children: Not prescribed
• Over 60: No special problems
• Driving and hazardous work: No problems expected
• Alcohol: No known problems