Atorvastatin

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Adco-Atorvastatin, Aspavor, Atolip, Dynator, Lipitor, Lipogen

Drug type:

Lipid-lowering drug - statin

Prescription needed:

Yes

What does it do?

Atorvastatin lowers blood cholesterol levels.

• Used to treat hypercholesterolaemia (high blood cholesterol levels) in patients who are at risk of heart disease, and have not responded to diet or lifestyle changes.
• Used to prevent heart attack or stroke in high risk diabetic patients.

How does it work?

Atorvastatin blocks the action of an enzyme in the liver that is needed for the manufacture of cholesterol.

How should it be used?

• A low-fat diet is usually recommended to help reduce cholesterol levels
• Do not drink more than 2 small glasses of grapefruit juice per day

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

Adult dosage range 10–80mg once daily

How quickly will it start to work?

Within 2 weeks, full beneficial effects within 4 weeks
  

How long will the effects last?

20–30 hours
                     

When should I stop using it?

Use as prescribed by your doctor

Is it safe for prolonged use?

Yes, but regular blood tests for liver function may be required

What are the possible side effects?

The following have been reported:

• More common: nausea, constipation, diarrhoea, headache, dizziness, tiredness, insomnia, back and joint pain. These are usually mild and transient.
• Report to your doctor before taking your next dose if you experience: persistent or severe muscle pain/weakness, jaundice, rash (these are all rare side effects)

OVERDOSE ACTION

Large overdoses may cause liver problems. Notify your doctor.

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver/kidney problems, alcohol abuse, underactive thyroid, family history of a muscle disorder, previous muscle problems or other reactions with other lipid lowering drugs
• Other medicines: Warfarin, macrolide antibiotics (e.g. erythromycin, clarithromycin), fusidic acid, antifungals, other lipid-lowering drugs, ciclosporin and other immuno-suppressant drugs, oral contraceptives, digoxin
• Pregnancy and breastfeeding: Not recommended, safety not established
• Children: Not recommended
• Over 60: No special problems
• Driving and hazardous work: No special problems
• Alcohol: Avoid excessive amounts, may increase the risk of liver problems