Calcipotriol

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Only available in combinations

Popular combinations:

Dovobet, Xamiol

Drug group:

Drug for psoriasis

Prescription needed?

Yes

What does it do?

Calcipotriol is used in the treatment of psoriasis, a condition characterised by areas of thickened, scaly plaques involving the skin of the body and scalp.

How does it work?

• Calcipotriol is a synthetic derivative of vitamin D
• It reduces production of the cells that cause skin thickening

How should it be used?

• Apply the appropriate form (cream/ointment/scalp solution) to the affected areas
• Wash your hands after application to avoid accidental transfer to unaffected areas
• Calcipotriol should not be used on the face
• Avoid excessive exposure to sunlight while using calcipotriol

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

• Apply to affected areas only, 1–2 x daily
• Maximum weekly adult dose: cream/ointment 100g, scalp solution 60ml (less if both preparations are used together)

How quickly will it start to work?

Improvement is usually seen within 2 weeks

How long will the effects last?

One application lasts up to 12 hours

When should I stop using it?

Do not stop without consulting your doctor, symptoms may recur

Is it safe for prolonged use?

Long term use in low doses provides beneficial effects.

If the effects seem to be declining after several weeks, treatment can be stopped for a few weeks and then restarted. Excessive prolonged use may lead to an increase in blood calcium levels, so regular checks on calcium levels in the blood or urine may be required.

What are the possible side effects?

The following have been reported:

• More common: temporary local irritation/itching, dry skin
• Less common: symptoms of high calcium levels (rash, thirst, frequent urination, nausea, constipation, abdominal pain, weakness, tiredness)
• Report to your doctor before taking your next dose if you experience: abdominal pain, weakness, tiredness, confusion, worsening of psoriasis

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: metabolic disorders, liver/kidney problems
• Other medicines: None known
• Pregnancy and breast-feeding: Safety not established
• Children: Not recommended under 6 years
• Over 60: No problems expected
• Driving and hazardous work: No problems expected
• Alcohol: No problems expected