Ergotamine

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular combinations:

Cafergot, Migril

Drug group:

Drug for migraine

Prescription needed:

Yes

What does it do?

• Used to treat migraines – restricted to when other treatments are ineffective, as newer agents with fewer side effects are now available
• It is also used in the prevention of cluster headaches

How does it work?

Ergotamine causes temporary narrowing of blood vessels

How should it be used?

• Ergotamine should be taken at the first sign of migraine (“aura”)
• Ergotamine is not for regular use - talk to your doctor if you have frequent migraine attacks as you may need more appropriate treatment
• Treatment should not be repeated within 4 days or more than twice a month

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

• Take one tablet at the onset of migraine, repeat after 30 minutes if needed
• 1–2mg per dose, maximum 4mg in 24 hours or 8mg in 1 week

How quickly will it start to work?

Within 15–30 minutes
                 

How long will the effects last?

Up to 24 hours
     

When should I stop using it?

Can be safely stopped as soon as no longer needed
     

Is it safe for prolonged use?

The recommended dosage and length of treatment should not be exceeded. Rebound headache may occur if it is taken too frequently.

What are the possible side effects?

The following have been reported:

• More common: abdominal pain, nausea, vomiting, muscle cramps
• Less common: cold/numb fingers and toes
• Report to your doctor before taking your next dose if you experience: dizziness, severe muscle pain/stiffness, severe diarrhoea, chest/leg/groin pain

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver/kidney/heart problems, poor circulation, high blood pressure, recent stroke, overactive thyroid gland, anaemia
• Other medicines: Beta blockers, sumatriptan and related drugs, erythromycin and related antibiotics, antivirals, oral contraceptives
• Pregnancy and breast-feeding: Not prescribed, can cause contractions of the uterus
• Children: Not usually prescribed
• Over 60: Not recommended
• Driving and hazardous work: Caution, the drug can cause dizziness
• Alcohol: No special problems
• Surgery and general anaesthetics: Notify your doctor if you have used ergotamine within 48 hours prior to surgery