Furosemide (Frusemide)

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Lasix, Puresis

Drug group:

Loop diuretic and antihypertensive drug

Prescription needed?

Yes

What does it do?

Furosemide is a diuretic used to treat:

• Oedema (accumulation of fluid in tissue spaces) – caused by heart failure, and lung/liver/kidney disorders
• Pulmonary oedema (fluid in the lungs) - used in emergency settings
• People with impaired kidney function because they do not respond well to thiazide diuretics

How does it work?

• Furosemide is a powerful, fast onset, short-acting loop diuretic
• It causes rapid fluid loss and can result in electrolyte imbalances eg. potassium loss

How should it be used?

• Potassium supplements or a potassium-sparing diuretic may be given with the drug
• If the above is not prescribed, eat plenty of potassium-rich fresh fruits and vegetables, such as bananas and tomatoes
• Do not take your dose too late in the day as you may need to get up during the night

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

• Tablets/liquid usually taken once daily in the morning
• Adult dose: 20–80mg daily, increased to a maximum of 2g daily if kidney function is impaired

How quickly will it start to work?

Within 1 hour, 5 minutes by injection          
         

How long will the effects last?

Up to 6 hours        

When should I stop using it?

Do not stop the drug without consulting your doctor  
                               

Is it safe for prolonged use?

Serious problems are unlikely. Your doctor may do regular blood tests to monitor kidney function and levels of potassium, sodium and calcium (may become depleted)        

What are the possible side effects?

Side effects of furosemide tend to diminish as your body adjusts.

The following have been reported:

• More common: dizziness, nausea, lethargy, muscle cramps
• Report to your doctor before taking your next dose if you experience: rash, photosensitivity, vomiting

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver/kidney problems, gout, previous allergic reaction to furosemide or sulphonamides, prostate problems
• Other medicines: Non-steroidal anti-inflammatory drugs (NSAIDs), lithium, digoxin, aminoglycoside, thiazide diuretics
• Pregnancy and breast-feeding: Safety in pregnancy not established, milk supply may be reduced
• Children: Reduced dose necessary
• Over 60: Reduced dose may be necessary
• Driving and hazardous work: Caution, the drug may reduce mental alertness and cause dizziness
• Alcohol: Keep consumption low, increased risk of dehydration and reduced blood pressure