Valsartan

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Diolo, Diovan, Migroben, Tareg, Zomevek

Popular combinations:

Co-Diovan, Exforge, Co Exforge, Co-Tareg, Copalia

Drug group:

Vasodilator and antihypertensive drug

Prescription needed?

Yes

What does it do?

• Valsartan is mainly used to treat hypertension (high blood pressure)
• It is also used to help prevent further complications after a myocardial infarction (heart attack) - prescribed alone or in combination with other post-myocardial infarction therapies such as aspirin, beta blockers, or statins

How does it work?

Valsartan is a type of vasodilator drug – it blocks the action of angiotensin II (a powerful hormone that constricts blood vessels). This relaxes the blood vessels, thereby lowering blood pressure and easing the heart’s workload.

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

• Hypertension: 20–320mg once daily, generally in the morning
• Post-myocardial infarction: 20-320mg, taken 2x daily

How quickly will it start to work?

Within 1–2 hours; full antihypertensive effect 2–4 weeks
              

How long will the effects last?

Antihypertensive effect lasts 24 hours      
  

When should I stop using it?

Do not stop taking the drug without consulting your doctor      
                              

Is it safe for prolonged use?

No special problems, but blood potassium levels and kidney function should be monitored.

What are the possible side effects?

The side effects of valsartan are usually mild and transient.

The following have been reported:

• More common: hypotension (low blood pressure), dizziness, headache, diarrhoea
• Less common: cough, muscle/joint/back pain
• Report to your doctor before taking your next dose if you experience: wheezing, swelling of the lips/tongue

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: renal artery stenosis, liver/kidney problems, angioedema
• Other medicines: other antihypertensives (vasodilators, diuretics), potassium supplements, ciclosporin, cimetidine, lithium, non-steroidal anti-inflammatory drugs (NSAIDs)
• Pregnancy and breast-feeding: Not prescribed in pregnancy (evidence of harm to the developing foetus), not recommended in breastfeeding
• Children: Not recommended
• Over 60: No special problems
• Driving and hazardous work: Caution, the drug can cause dizziness or drowsiness
• Alcohol: Avoid, enhanced blood-pressure-lowering and other side effects