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Loratadine/Desloratadine

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

 

Popular brand names:

[loratadine] Allergex Non Drowsy, AP-Loratidine, Clarinese, Clarityne

[desloratadine] Dazit, Deselex, Neoloridin 5, Neoclarityne

Drug group:

Antihistamine

Prescription needed?

No

 

What does it do?

Loratadine and desloratidine are long-acting antihistamine drugs used in the treatment of:

  • Allergic rhinitis – relives sneezing, nasal discharge, and itching/burning of the eyes
  • Allergic skin conditions - such as chronic urticaria (itching)

 

How should it be used?

Stop using Loratadine/desloratadine 4-5 days before skin prick allergy testing as the drugs may influence the results.

 

What is the typical dosage?

Follow instructions on the label. Call your doctor if symptoms worsen.

Adults: loratadine 10mg once daily; desloratadine 5mg once daily

 

How quickly will it start to work?

Usually within 1 hour     
              

How long will the effects last?

Up to 24 hours     

When should I stop using it?

Can be safely stopped as no longer needed   
 

Is it safe for prolonged use?

No problems expected                                                                   

 

What are the possible side effects?

Side effects with loratadine/desloratadine are rare.

The following have been reported:

  • Less common: fatigue, nausea, headache, dry mouth
  • Report to your doctor before taking your next dose if you experience: palpitations, fainting 

 

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

  • Certain health problems: liver disease
  • Other medicines: cimetidine, clarithromycin, erythromycin, ketoconazole, fluoxetine, fluconazole, quinidine, fosamprenavir
  • Pregnancy and breast-feeding: Safety not established
  • Children: Not recommended under 2 years (loratadine) / under 1 year (desloratadine)
  • Over 60: No problems expected
  • Driving and hazardous work: Caution, the drug can cause fatigue
  • Alcohol: Caution, enhanced sedative effects


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