Desloratadine/Loratadine

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

[loratadine] Allergex Non Drowsy, AP-Loratidine, Clarinese, Clarityne;

[desloratadine] Dazit, Deselex, Neoloridin 5, Neoclarityne

Drug group:

Antihistamine

Prescription needed?

No

What does it do?

Loratadine and desloratidine are long-acting antihistamine drugs used in the treatment of:

• Allergic rhinitis – relives sneezing, nasal discharge, and itching/burning of the eyes
• Allergic skin conditions - such as chronic urticaria (itching)

How should it be used?

Stop using Loratadine/desloratadine 4-5 days before skin prick allergy testing as the drugs may influence the results

What is the typical dosage?

Follow instructions on the label. Call your doctor if symptoms worsen.

• Adults: loratadine 10mg once daily; desloratadine 5mg once daily

How quickly will it start to work?

Usually within 1 hour
                   

How long will the effects last?

Up to 24 hours
     

When should I stop using it?

Can be safely stopped as no longer needed
     

Is it safe for prolonged use?

No problems expected                                                                   

What are the possible side effects?

Side effects with loratadine/desloratadine are rare.

The following have been reported:

• Less common: fatigue, nausea, headache, dry mouth
• Report to your doctor before taking your next dose if you experience: palpitations, fainting 

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver disease
• Other medicines: cimetidine, clarithromycin, erythromycin, ketoconazole, fluoxetine, fluconazole, quinidine, fosamprenavir
• Pregnancy and breast-feeding: Safety not established
• Children: Not recommended under 2 years (loratadine) / under 1 year (desloratadine)
• Over 60: No problems expected
• Driving and hazardous work: Caution, the drug can cause fatigue
• Alcohol: Caution, enhanced sedative effects