Amlodipine

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Amlate, Amloc, Amtas, Ciplavasc, Lomanor, Norvasc

Popular combinations:

Coveram, Exforge, Twynsta

Drug type:

Anti-angina, antihypertensive

Prescription needed:

Yes

What does it do?

Used in the treatment of angina (attacks of chest pain) and hypertension (high blood pressure)

How does it work?

• Amlodipine is a calcium channel blocker
• It interferes with the conduction of signals in the muscles of the heart and blood vessels

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

5–10mg, once daily

How quickly will it start to work?

Within 6–12 hours
                     

How long will the effects last?

24 hours

When should I stop using it?

Use as directed by your doctor
       

Is it safe for prolonged use?

Yes

What are the possible side effects?

The following have been reported:

• More common: dizziness on standing, leg and ankle swelling, headache, fatigue, and flushing
• Report to your doctor before taking your next dose if you experience: palpitations, nausea, abdominal pain, a rash, or breathing difficulties, worsening angina (rare)

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver problems, heart failure or aortic stenosis, diabetes
• Other medicines: Ketoconazole, itraconazole, ritonavir, St John’s wort, alpha blockers, beta blockers, ACE inhibitors, diuretics, some antimalarials
• Pregnancy and breastfeeding: Safety not established
• Children: Not recommended
• Over 60: No special problems
• Driving and hazardous work: caution, the drug can cause dizziness
• Surgery and general anaesthetics Amlodipine may interact with some general anaesthetics causing a fall in blood pressure
• Alcohol: Avoid, alcohol may further reduce blood pressure
• Certain foods: avoid grapefruit juice