Fluoxetine

Please note: these are basic guidelines, refer to your doctor for a professional medical opinion.

Popular brand names:

Lilly-fluoxetine, Lorien, Nuzak, Prozac

Drug group:

Antidepressant drug, SSRI

Prescription needed?

Yes

What does it do?

Fluoxetine is an SSRI (selective serotonin re-uptake inhibitor) type antidepressants used to treat:

• Depression (main use) – elevates mood and restores interest in everyday pursuits
• Bulimia nervosa – helps to reduce binge eating and purging activity
• Obsessive-compulsive disorder

How should it be used?

Fluoxetine works best if taken in the morning and no doses are missed

What is the typical dosage?

Your doctor will recommend a dosage tailored to your need, but typically:

Adult dose: 20–60mg taken once daily

How quickly will it start to work?

Some benefits in 14 days, but full benefits from 6 weeks. Obsessive-compulsive disorder and bulimia may take longer to respond.

How long will the effects last?

Beneficial effects for up to 6 weeks following prolonged treatment.

When should I stop using it?

Do not stop the drug without consulting your doctor, you may need to reduce your dose gradually.

Is it safe for prolonged use?

No problems expected in adults, side effects decrease with time. Children/adolescents: small risk of suicidal thoughts and self-harm, monitor closely.

Any person experiencing drowsiness, confusion, muscle cramps, or seizures should be monitored for low sodium levels in the blood.                                                

What are the possible side effects?

Most side effects are transient and usually wear off in 1–2 weeks.

The following have been reported:

• More common: restlessness, anxiety, insomnia, nausea, vomiting, headache
• Less common: sedation, sexual dysfunction
• Report to your doctor before taking your next dose if you experience: rash, suicidal thoughts or attempts

What other considerations are important?

Dosage may be adjusted by your doctor under certain conditions.

• Certain health problems: liver/kidney problems, history of mania, diabetes, epilepsy/seizures, previous allergic reaction to fluoxetine or other SSRIs
• Other medicines: other sedative drugs, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, antipsychotics
• Pregnancy and breast-feeding: Avoid if possible, discuss with your doctor
• Children: Not generally recommended under 18 years
• Over 60: Reduced dose may be necessary
• Driving and hazardous work: Caution, the drug can cause drowsiness and affect your judgement and coordination
• Alcohol: No special problems